Angiotensin I (human)

Description:

This human Angiotensin I (Ang I) sequence also corresponds to horse, sheep, pig, and rat Ang I. It is cleaved by angiotensin-converting enzyme (ACE) yielding Ang II and the dipeptide His-Leu.

Sequence:

DRVYIHPFHL

General

References

Comments (0)

Name	Angiotensin I (human)
Category	Angiotensins and Related Peptides
One Letter Code	DRVYIHPFHL
Three Letter Code	{Asp}{Arg}{Val}{Tyr}{Ile}{His}{Pro}{Phe}{His}{Leu}
Molecular Weight	1296.500
Application	Cardiovascular System & Diseases

Lundequist, Anders, et al. "Cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin II." Journal of Biological Chemistry 279.31 (2004): 32339-32344.

Olson, Susan, et al. "Angiotensin II stimulates nitric oxide production in pulmonary artery endothelium via the type 2 receptor." American Journal of Physiology-Lung Cellular and Molecular Physiology 287.3 (2004): L559-L568.

Ahmad, Sarfaraz, et al. "Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue." PloS one 6.12 (2011).