Hel 13-5

Description:

Hel 13-5 is a most efficient DNA and siRNA delivering and transfecting agent.

Sequence:

KLLKLLLKLWLKLLKLLL

General

References

Comments (0)

Name	Hel 13-5
Category	Cell Permeable Peptides (CPP) / Drug Delivery Peptides
One Letter Code	KLLKLLLKLWLKLLKLLL
Three Letter Code	{Lys}{Leu}{Leu}{Lys}{Leu}{Leu}{Leu}{Lys}{Leu}{Trp}{Leu}{Lys}{Leu}{Leu}{Lys}{Leu}{Leu}{Leu}
Molecular Weight	2203.010
Application	Cell-permeable Peptides

Nakamura, Yoshihiro, et al. "Improvement of pulmonary surfactant activity by introducing D-amino acids into highly hydrophobic amphiphilic α-peptide Hel 13-5." Biochimica et Biophysica Acta (BBA)-Biomembranes 1838.8 (2014): 2046-2052.

Nakahara, Hiromichi, Sannamu Lee, and Osamu Shibata. "Pulmonary surfactant model systems catch the specific interaction of an amphiphilic peptide with anionic phospholipid." Biophysical journal 96.4 (2009): 1415-1429.

Kitamura, Akiko, et al. "Morphological behavior of acidic and neutral liposomes induced by basic amphiphilic α-helical peptides with systematically varied hydrophobic-hydrophilic balance." Biophysical journal 76.3 (1999): 1457-1468.

Ohmori, Naoya, et al. "Importance of hydrophobic region in amphiphilic structures of α-helical peptides for their gene transfer-ability into cells." Biochemical and biophysical research communications 245.1 (1998): 259-265.

Kiyota, Taira, Sannamu Lee, and Gohsuke Sugihara. "Design and Synthesis of Amphiphilic α-Helical Model Peptides with Systematically Varied Hydrophobic− Hydrophilic Balance and Their Interaction with Lipid-and Bio-Membranes." Biochemistry 35.40 (1996): 13196-13204.