Aminopeptidase N Ligand (CD13), NGR peptide

Description:

The NGR (Asn-Gly-Arg) peptide motif is an aminopeptidase N (CD13) ligand that targets angiogenic blood vessels.

Sequence:

CNGRCG (Disulfide bridge: 1 - 5)

General

References

Comments (0)

Name	Aminopeptidase N Ligand (CD13), NGR peptide
Category	Cell Permeable Peptides (CPP) / Drug Delivery Peptides
One Letter Code	CNGRCG (Disulfide bridge: 1 - 5)
Three Letter Code	{Cys}{Asn}{Gly}{Arg}{Cys}{Gly} (Disulfide bridge: 1-5) (Disulfide bridge: 1 - 5)
Molecular Weight	606.700
Application	Cell-permeable Peptides

Curnis, Flavio, et al. "Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells." Cancer research 62.3 (2002): 867-874.

Curnis, Flavio, Angelina Sacchi, and Angelo Corti. "Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration." The Journal of clinical investigation 110.4 (2002): 475-482.