Z - DEVD - AFC

Description:

AFC (7-amino-4-trifluoromethylcoumarin)-derived caspase substrates are widely used for the fluorimetric detection of various caspase activities.

Sequence:

Z-DEVD-AFC

General

References

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Name	Z - DEVD - AFC
Category	Caspase Related Peptides
One Letter Code	Z-DEVD-AFC
Three Letter Code	z-{Asp}{Glu}{Val}{Asp}-AFC
Molecular Weight	821.600
Application	Apoptosis & Necrosis

Gurtu, Vanessa, Steven R. Kain, and Guohong Zhang. "Fluorometric and colorimetric detection of caspase activity associated with apoptosis." Analytical biochemistry 251.1 (1997): 98-102.

Martins, Luis M., et al. "Activation of multiple interleukin-1β converting enzyme homologues in cytosol and nuclei of HL-60 cells during etoposide-induced apoptosis." Journal of Biological Chemistry 272.11 (1997): 7421-7430.