Caspase 3 (Apopain) Substrate 1m, fluorogenic

Description:

AMC (7-amino-4-methylcoumarin)-derived caspase substrates are widely used for the fluorimetric detection of various caspase activities.

Sequence:

Ac-DEVD-AMC
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  • Name Caspase 3 (Apopain) Substrate 1m, fluorogenic
    Category Caspase Related Peptides
    One Letter Code Ac-DEVD-AMC
    Three Letter Code Acetylation-{Asp}{Glu}{Val}{Asp}-AMC
    Molecular Weight 675.500
    Application Apoptosis & Necrosis
    Bugueno, Isaac Maximiliano, et al. "Porphyromonas gingivalis differentially modulates cell death profile in ox-LDL and TNF-α pre-treated endothelial cells." PloS one 11.4 (2016).
    Rueda-Rincon, Natalia, et al. "p53 attenuates AKT signaling by modulating membrane phospholipid composition." Oncotarget 6.25 (2015): 21240.
    Hattermann, Kirsten, et al. "Effects of the chemokine CXCL12 and combined internalization of its receptors CXCR4 and CXCR7 in human MCF-7 breast cancer cells." Cell and tissue research 357.1 (2014): 253-266.
    Abdi, Jahangir, et al. "Stimulation of Toll-like receptor-1/2 combined with Velcade increases cytotoxicity to human multiple myeloma cells." Blood cancer journal 3.5 (2013): e119-e119.
    Naves, Thomas, et al. "Autophagy takes place in mutated p53 neuroblastoma cells in response to hypoxia mimetic CoCl2." Biochemical pharmacology 85.8 (2013): 1153-1161.
    Durieux, Anne‐Cécile, et al. "A centronuclear myopathy–dynamin 2 mutation impairs autophagy in mice." Traffic 13.6 (2012): 869-879.
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