Caspase 3 (Apopain) Substrate 1f, fluorogenic

Description:

AFC (7-amino-4-trifluoromethylcoumarin)-derived caspase substrates are widely used for the fluorimetric detection of various caspase activities.

Sequence:

Ac-DEVD-AFC

General

References

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Name	Caspase 3 (Apopain) Substrate 1f, fluorogenic
Category	Caspase Related Peptides
One Letter Code	Ac-DEVD-AFC
Three Letter Code	Acetylation-{Asp}{Glu}{Val}{Asp}-AFC
Molecular Weight	729.500
Application	Apoptosis & Necrosis

Clancy, Danielle M., et al. "Production of biologically active IL‐36 family cytokines through insertion of N‐terminal caspase cleavage motifs." FEBS open bio 6.4 (2016): 338-348.

Anter, Jaouad, et al. "Evaluation of potential antigenotoxic, cytotoxic and proapoptotic effects of the olive oil by-product “alperujo”, hydroxytyrosol, tyrosol and verbascoside." Mutation Research/Genetic Toxicology and Environmental Mutagenesis 772 (2014): 25-33.

Butinar, Miha, et al. "Stefin B deficiency reduces tumor growth via sensitization of tumor cells to oxidative stress in a breast cancer model." Oncogene 33.26 (2014): 3392-3400.

Gobec, Martina, et al. "Structural characterization and biological evaluation of a clioquinol–ruthenium complex with copper-independent antileukaemic activity." Dalton Transactions 43.24 (2014): 9045-9051.

Jerič, Barbara, et al. "N-terminally truncated forms of human cathepsin F accumulate in aggresome-like inclusions." Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833.10 (2013): 2254-2266.

Baiz, Daniele, et al. "Synthesis and characterization of a novel prostate cancer-targeted phosphatidylinositol-3-kinase inhibitor prodrug." Journal of medicinal chemistry 55.18 (2012): 8038-8046.