Caspase 1 (ICE) Substrate 2, chromogenic

Description:

pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric determination of caspase activity.

Sequence:

Ac-YVAD-pNA

General

References

Comments (0)

Name	Caspase 1 (ICE) Substrate 2, chromogenic
Category	Caspase Related Peptides
One Letter Code	Ac-YVAD-pNA
Three Letter Code	Acetylation-{Tyr}{Val}{Ala}{Asp}-p-Nitroanilide
Molecular Weight	628.600
Application	Apoptosis & Necrosis

Grütter, Markus G. "Caspases: key players in programmed cell death." Current opinion in structural biology 10.6 (2000): 649-655.

Gastman, Brian R. "Apoptosis and its clinical impact." Head & neck 23.5 (2001): 409-425.

Grütter, Markus G. "Caspases: key players in programmed cell death." Current opinion in structural biology 10.6 (2000): 649-655.

Koeplinger, Kenneth A., et al. "Caspase 8: an efficient method for large-scale autoactivation of recombinant procaspase 8 by matrix adsorption and characterization of the active enzyme." Protein expression and purification 18.3 (2000): 378-387.

Dall, Elfriede, and Hans Brandstetter. "Activation of legumain involves proteolytic and conformational events, resulting in a context-and substrate-dependent activity profile." Acta Crystallographica Section F: Structural Biology and Crystallization Communications 68.1 (2012): 24-31.

Cooley, Jessica, et al. "The serpin MNEI inhibits elastase-like and chymotrypsin-like serine proteases through efficient reactions at two active sites." Biochemistry 40.51 (2001): 15762-15770.