Caspase 9 Substrate 1, chromogenic

Description:

pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric determination of caspase activity.

Sequence:

Ac-LEHD-pNA
  • General
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  • Name Caspase 9 Substrate 1, chromogenic
    Category Caspase Related Peptides
    One Letter Code Ac-LEHD-pNA
    Three Letter Code Acetylation-{Leu}{Glu}{His}{Asp}-p-Nitroanilide
    Molecular Weight 674.700
    Application
    Grütter, Markus G. "Caspases: key players in programmed cell death." Current opinion in structural biology 10.6 (2000): 649-655.
    Gastman, Brian R. "Apoptosis and its clinical impact." Head & neck 23.5 (2001): 409-425.
    Koeplinger, Kenneth A., et al. "Caspase 8: an efficient method for large-scale autoactivation of recombinant procaspase 8 by matrix adsorption and characterization of the active enzyme." Protein expression and purification 18.3 (2000): 378-387.
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