Caspase 8 Substrate 1, chromogenic

Description:

pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric determination of caspase activity.

Sequence:

Ac-IETD-pNA

General

References

Comments (0)

Name	Caspase 8 Substrate 1, chromogenic
Category	Caspase Related Peptides
One Letter Code	Ac-IETD-pNA
Three Letter Code	Acetylation-{Ile}{Glu}{Thr}{Asp}-p-Nitroanilide
Molecular Weight	638.600
Application	Apoptosis & Necrosis

Gastman, Brian R. "Apoptosis and its clinical impact." Head & neck 23.5 (2001): 409-425.

Grütter, Markus G. "Caspases: key players in programmed cell death." Current opinion in structural biology 10.6 (2000): 649-655.

Koeplinger, Kenneth A., et al. "Caspase 8: an efficient method for large-scale autoactivation of recombinant procaspase 8 by matrix adsorption and characterization of the active enzyme." Protein expression and purification 18.3 (2000): 378-387.

Pandey, Kailash C., et al. "Falstatin, a cysteine protease inhibitor of Plasmodium falciparum, facilitates erythrocyte invasion." PLoS pathogens 2.11 (2006).

Kilic, M., et al. "Formation of noncanonical high molecular weight caspase-3 and-6 complexes and activation of caspase-12 during serum starvation induced apoptosis in AKR-2B mouse fibroblasts." Cell Death & Differentiation 9.2 (2002): 125-137.

Hennino, Ana, et al. "Regulation of the Fas death pathway by FLICE-inhibitory protein in primary human B cells." The Journal of Immunology 165.6 (2000): 3023-3030.