Caspase 3 (Apopain) Substrate 1, chromogenic

Description:

pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric determination of caspase activity.

Sequence:

Ac-DEVD-pNA

General

References

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Name	Caspase 3 (Apopain) Substrate 1, chromogenic
Category	Caspase Related Peptides
One Letter Code	Ac-DEVD-pNA
Three Letter Code	Acetylation-{Asp}{Glu}{Val}{Asp}-p-Nitroanilide
Molecular Weight	638.500
Application	Apoptosis & Necrosis

Castro-Caldas, Margarida, et al. "GSTpi expression in MPTP-induced dopaminergic neurodegeneration of C57BL/6 mouse midbrain and striatum." Journal of molecular neuroscience 38.2 (2009): 114-127.

Okun, Eitan, et al. "The organotellurium compound ammonium trichloro (dioxoethylene‐o, o′) tellurate reacts with homocysteine to form homocystine and decreases homocysteine levels in hyperhomocysteinemic mice." The FEBS journal 274.12 (2007): 3159-3170.

Kuperstein, Faina, Annette Brand, and Ephraim Yavin. "Amyloid Aβ1− 40 preconditions non‐apoptotic signals in vivo and protects fetal rat brain from intrauterine ischemic stress." Journal of neurochemistry 91.4 (2004): 965-974.

Kuperstein, Faina, and Ephraim Yavin. "Pro‐apoptotic signaling in neuronal cells following iron and amyloid beta peptide neurotoxicity." Journal of neurochemistry 86.1 (2003): 114-125.

Ruefli, Astrid A., et al. "Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P‐glycoprotein‐expressing cells." International journal of cancer 99.2 (2002): 292-298.