Ac-Tyr-Val-Ala-Asp-AMC

Description:

Ac-YVAD-AMC is a fluorogenic substrate for caspase-1 (ICE).

Sequence:

Ac-YVAD-AMC
  • General
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  • Name Ac-Tyr-Val-Ala-Asp-AMC
    Category Caspase Inhibitors and Substrates
    One Letter Code Ac-YVAD-AMC
    Three Letter Code Ac-{Tyr}{Val}{Ala}{Asp}-AMC
    Molecular Weight 665.700
    Application Apoptosis & Necrosis
    Bugueno, Isaac Maximiliano, et al. "Porphyromonas gingivalis differentially modulates cell death profile in ox-LDL and TNF-α pre-treated endothelial cells." PloS one 11.4 (2016).
    Julián, Israel, et al. "Phylogenetically distant barley legumains have a role in both seed and vegetative tissues." Journal of experimental botany 64.10 (2013): 2929-2941.
    Yordanova, Zhenya P., et al. "Mastoparan-induced programmed cell death in the unicellular alga Chlamydomonas reinhardtii." Annals of botany 111.2 (2013): 191-205.
    Bianchi, Giada, et al. "The proteasome load versus capacity balance determines apoptotic sensitivity of multiple myeloma cells to proteasome inhibition." Blood, The Journal of the American Society of Hematology 113.13 (2009): 3040-3049.
    He, Rui, et al. "Metacaspase-8 modulates programmed cell death induced by ultraviolet light and H2O2 in Arabidopsis." Journal of Biological Chemistry 283.2 (2008): 774-783.
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