Ac-Tyr-Val-Ala-Asp-AFC

Description:

The presence of halogen substituents at the fluorescent group improves membrane permeability of the YVAD-derived caspase-1 substrate.

Sequence:

Ac-YVAD-AFC

General

References

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Name	Ac-Tyr-Val-Ala-Asp-AFC
Category	Caspase Inhibitors and Substrates
One Letter Code	Ac-YVAD-AFC
Three Letter Code	Acetylation-{Tyr}{Val}{Ala}{Asp}-AFC
Molecular Weight	719.670
Application	Apoptosis & Necrosis

Xiang, Jialing, Debra T. Chao, and Stanley J. Korsmeyer. "BAX-induced cell death may not require interleukin 1β-converting enzyme-like proteases." Proceedings of the National Academy of Sciences 93.25 (1996): 14559-14563.