Thrombospondin - derived Peptide; Cyclic CSVTCG

Description:

This peptide is derived from thrombospondin. It is cyclized through a disulfide bond. Thrombospondin is a matrix-bound glycoprotein involved in cancer metastasis, tumor adhesion, and angiogenesis. This peptide has been shown to competitively inhibit platelet aggregation and tumor metastasis.

Sequence:

CSVTCG (Disulfide bridge: 1-5)

General

References

Comments (0)

Name	Thrombospondin - derived Peptide; Cyclic CSVTCG
Category	Cardiovascular Related Peptides
One Letter Code	CSVTCG (Disulfide bridge: 1-5)
Three Letter Code	{Cys}{Ser}{Val}{Thr}{Cys}{Gly} (Disulfide bridge: 1-5) (Disulfide bridge: 1-5)
Molecular Weight	566.700
Application	Cancer Research Peptides, Cell Adhesion Peptides, Thrombospondins

Wakiyama, T., et al. "The localization of thrombospondin-1 (TSP-1), cysteine-serine-valine-threonine-cysteine-glycine (CSVTCG) TSP receptor, and matrix metalloproteinase-9 (MMP-9) in colorectal cancer." Histology and histopathology 16.2 (2001): 345-352.

Asch, Adam S., et al. "Thrombospondin sequence motif (CSVTCG) is responsible for CD36 binding." Biochemical and biophysical research communications 182.3 (1992): 1208-1217.