[Pyr1] - Apelin - 13

Description:

Apelin -13 is a vasoactive peptide and one of the most effective endogenous inotropic agents known. [125I]-(Pyr1)Apelin-13 binds with high affinity and selectivity to human cardiac tissue.

Sequence:

{pGLU}RPRLSHKGPMPF-OH

General

References

Comments (0)

Name	[Pyr1] - Apelin - 13
Category	Cardiovascular Related Peptides
One Letter Code	{pGLU}RPRLSHKGPMPF-OH
Three Letter Code	{pGLU}Arg}{Pro}{Arg}{Leu}{Ser}{His}{Lys}{Gly}{Pro}{Met}{Pro}{Phe}
Molecular Weight	1533.800
Application	Cardiovascular System & Diseases

Katugampola, Sidath D., et al. "[125I]‐(Pyr1) Apelin‐13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man." British journal of pharmacology 132.6 (2001): 1255-1260.

Tatemoto, Kazuhiko, et al. "Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor." Biochemical and biophysical research communications 251.2 (1998): 471-476.