Neurotensin

Description:

This 13 amino acid peptide was first isolated from bovine hypothalamus. Neurotensin has been implicated in the pathophysiology of schizophrenia, Huntington, and Parkinson diseases.

Sequence:

{pGLU}LYENKPRRPYIL

General

References

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Name	Neurotensin
Category	Cardiovascular Related Peptides
One Letter Code	{pGLU}LYENKPRRPYIL
Three Letter Code	{pGLU}Leu}{Tyr}{Glu}{Asn}{Lys}{Pro}{Arg}{Arg}{Pro}{Tyr}{Ile}{Leu}
Molecular Weight	1672.920
Application	Neuropeptide Y (NPY)

Fälth, Maria, et al. "SwePep, a database designed for endogenous peptides and mass spectrometry." Molecular & Cellular Proteomics 5.6 (2006): 998-1005.

Huang, Kai-Fa, et al. "Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation." Proceedings of the National Academy of Sciences 102.37 (2005): 13117-13122.

Eriste, Elo, et al. "A novel form of neurotensin post-translationally modified by arginylation." Journal of Biological Chemistry 280.42 (2005): 35089-35097.