Sauvagine

Description:

It's 40 amino acids in length that funcutions as neuropeptide.It was originally isolated from the skin of the frog Phyllomedusa sauvagei.It affects diuresis in the cardiovascular system and causes the release of ACTH and endorphins.

Sequence:

{pGLU}GPPISIDLSLELLRKMIEIEKQEKEKQQAANNRLLLDTI-NH2
  • General
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  • Name Sauvagine
    Category Cardiovascular Related Peptides
    One Letter Code {pGLU}GPPISIDLSLELLRKMIEIEKQEKEKQQAANNRLLLDTI-NH2
    Three Letter Code {pGLU}Gly}{Pro}{Pro}{Ile}{Ser}{Ile}{Asp}{Leu}{Ser}{Leu}{Glu}{Leu}{Leu}{Arg}{Lys}{Met}{Ile}{}{Glu}{Ile}{Glu}{Lys}{Gln}{Glu}{Lys}{Glu}{Lys}{Gln}{Gln}{Ala}{Ala}{Asn}{Asn}{Arg}{Leu}{Leu}{Leu}{Asp}{Thr}{Ile}-NH2
    Molecular Weight 4599.400
    Application Cardiovascular System & Diseases
    MONTECUCCHI, PIER CARLO, and LUIGIA GOZZINI. "Secondary structure prediction of sauvagine, a novel biologically active polypeptide from a frog." International journal of peptide and protein research 20.2 (1982): 139-143.
    Erspamer, Vittorio, and Pietro Melchiorri. "Active polypeptides: from amphibian skin to gastrointestinal tract and brain of mammals." Trends in pharmacological sciences 1.2 (1980): 391-395.
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