HOE I40

Description:

Hoe 140 is a stable B2 bradykinin antagonist. Hoe 140 is used to evaluate the role of bradykinin in human diseases because of its high potency and good tolerability.

Sequence:

{D-Arg}RP{Hyp}G{Thi}S{D-Tic}{Oic}R
  • General
  • References
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  • Name HOE I40
    Category Cardiovascular Related Peptides
    One Letter Code {D-Arg}RP{Hyp}G{Thi}S{D-Tic}{Oic}R
    Three Letter Code {D-Arg}{Arg}{Pro}{Hyp}{Gly}{Thi}{Ser}{D-Tic}{Oic}{Arg}
    Molecular Weight 1304.500
    Application Cardiovascular System & Diseases
    Hall, Judith M. "Bradykinin receptors." General pharmacology 28.1 (1997): 1-6.
    Yamaguchi-Sase, S., et al. "Amelioration of hyperalgesia by kinin receptor antagonists or kininogen deficiency in chronic constriction nerve injury in rats." Inflammation Research 52.4 (2003): 164-169.
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