Proadrenomedullin N - terminal 20 peptide, PAMP (1 - 20)

Description:

PAMP (1-20) is a biologically active molecule produced by posttranslational processing of proadrenomedullin. It is involved in many physiological processes, including vasodilation, bronchodilation, hormone secretion, cell migration, apoptosis, and angiogenesis.

Sequence:

ARLDVASEFRKKWNKWALSR-NH3
  • General
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  • Name Proadrenomedullin N - terminal 20 peptide, PAMP (1 - 20)
    Category Cardiovascular Related Peptides
    One Letter Code ARLDVASEFRKKWNKWALSR-NH3
    Three Letter Code {Ala}{Arg}{Leu}{Asp}{Val}{Ala}{Ser}{Glu}{Phe}{Arg}{Lys}{Lys}{Trp}{Asn}{Lys}{Trp}{Ala}{Leu}{Ser}{Arg}{NH2
    Molecular Weight 2460.900
    Application Cardiovascular System & Diseases
    Mahata, Manjula, et al. "Proadrenomedullin N-terminal 20 peptide: minimal active region to regulate nicotinic receptors." Hypertension 32.5 (1998): 907-916.
    Kamohara, Masazumi, et al. "Identification of MrgX2 as a human G-protein-coupled receptor for proadrenomedullin N-terminal peptides." Biochemical and biophysical research communications 330.4 (2005): 1146-1152.
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