[Asp370] - Tyrosinase (368 - 376)

Description:

This tumor antigenic peptide is a tyrosinase fragment presented by HLA-A2 antigen to CTLs.

Sequence:

YMDGTMSQV

General

References

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Name	[Asp370] - Tyrosinase (368 - 376)
Category	Cancer Research Peptides
One Letter Code	YMDGTMSQV
Three Letter Code	{Tyr}{Met}{Asp}{Gly}{Thr}{Met}{Ser}{Gln}{Val}
Molecular Weight	1031.200
Application	Cancer Research

Chapiro, Jacques, et al. "Destructive cleavage of antigenic peptides either by the immunoproteasome or by the standard proteasome results in differential antigen presentation." The Journal of Immunology 176.2 (2006): 1053-1061.

Paczesny, Sophie, et al. "Expansion of melanoma-specific cytolytic CD8+ T cell precursors in patients with metastatic melanoma vaccinated with CD34+ progenitor-derived dendritic cells." The Journal of experimental medicine 199.11 (2004): 1503-1511.

Lee, P., et al. "Effects of interleukin-12 on the immune response to a multipeptide vaccine for resected metastatic melanoma." Journal of Clinical Oncology 19.18 (2001): 3836-3847.