(Ser(PO₃H₂)⁵¹⁶)-Artemis (511-523)

Description:

Artemis is a phospho-protein that has been shown to have roles in V(D)J recombination, nonhomologous end-joining of double-strand breaks, and regulation of the DNA damage-induced G2/M cell cycle checkpoint.

Sequence:

TVAGG(p)SQSPKLFS
  • General
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  • Name (Ser(PO₃H₂)⁵¹⁶)-Artemis (511-523)
    Category Cancer Research Peptides
    One Letter Code TVAGG(p)SQSPKLFS
    Three Letter Code {Thr}{Val}{Ala}{Gly}{Gly}{Ser(PO₃H₂)}{Gln}{Ser}{Pro}{Lys}{Leu}{Phe}{Ser}
    Molecular Weight 1358.410
    Application Cancer Research
    Wu, Xian-Jie, et al. "Expression and location of phospho-Artemis (Serine516) in hair follicles during induced growth of mouse hair." Archives of dermatological research 304.4 (2012): 319-324.
    Sun, Xiaonan, et al. "Identification and characterization of a small inhibitory peptide that can target DNA-PKcs autophosphorylation and increase tumor radiosensitivity." International Journal of Radiation Oncology* Biology* Physics 84.5 (2012): 1212-1219.
    Geng, Liyi, Catherine J. Huntoon, and Larry M. Karnitz. "RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network." Journal of Cell Biology 191.2 (2010): 249-257.
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