H-Thr-Pro-Asn-Gln-Arg-Gln-Asn-Val-Cys-OH

Description:

The nonapeptide TPNQRQNVC peptide is the naturally presented epitope at the cell surface by HLA-B7 molecules recognized by CTL RP1

Sequence:

TPNQRQNVC
  • General
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  • Name H-Thr-Pro-Asn-Gln-Arg-Gln-Asn-Val-Cys-OH
    Category Cancer Research Peptides
    One Letter Code TPNQRQNVC
    Three Letter Code {Thr}{Pro}{Asn}{Gln}{Arg}{Gln}{Asn}{Val}{Cys}
    Molecular Weight 1059.170
    Application Cancer Research
    Bleakley, Marie, and Stanley R. Riddell. "Exploiting T cells specific for human minor histocompatibility antigens for therapy of leukemia." Immunology and cell biology 89.3 (2011): 396-407.
    de Rijke, Björn, et al. "A frameshift polymorphism in P2X5 elicits an allogeneic cytotoxic T lymphocyte response associated with remission of chronic myeloid leukemia." The Journal of clinical investigation 115.12 (2005): 3506-3516.
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