H-Leu-Ser-Pro-Phe-Pro-Phe-Asp-Leu-OH

Description:

P2Ca, an octapeptide derived from α-ketoglutarate dehydrogenase isolated from tissues of H-2d mice.

Sequence:

LSPFPFDL

General

References

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Name	H-Leu-Ser-Pro-Phe-Pro-Phe-Asp-Leu-OH
Category	Cancer Research Peptides
One Letter Code	LSPFPFDL
Three Letter Code	{Leu}{Ser}{Pro}{Phe}{Pro}{Phe}{Asp}{Leu}
Molecular Weight	935.090
Application	Cancer Research

Engels, Boris, et al. "Long-term persistence of CD4+ but rapid disappearance of CD8+ T cells expressing an MHC class I-restricted TCR of nanomolar affinity." Molecular Therapy 20.3 (2012): 652-660.

Kageyama, Shigeki, et al. "Potent cytolytic response by a CD8+ CTL clone to multiple peptides from the same protein in association with an allogeneic class I MHC molecule." The Journal of Immunology 166.5 (2001): 3028-3034.

Lebowitz, Michael S., et al. "Soluble, high-affinity dimers of T-cell receptors and class II major histocompatibility complexes: biochemical probes for analysis and modulation of immune responses." Cellular immunology 192.2 (1999): 175-184.

O'Herrin, Sean M., et al. "Analysis of the expression of peptide–major histocompatibility complexes using high affinity soluble divalent T cell receptors." The Journal of experimental medicine 186.8 (1997): 1333-1345.

Dutz, Jan P., et al. "A cytotoxic T lymphocyte clone can recognize the same naturally occurring self peptide in association with a self and a nonself class I MHC protein." Molecular immunology 31.13 (1994): 967-975.