gp100 (25 - 33) (human)

Description:

This is amino acids 25 to 33 fragment of human melanoma antigen gp100. This H-2Db restricted epitope is recognized by T cells.

Sequence:

KVPRNQDWL

General

References

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Name	gp100 (25 - 33) (human)
Category	Cancer Research Peptides
One Letter Code	KVPRNQDWL
Three Letter Code	{Lys}{Val}{Pro}{Arg}{Asn}{Gln}{Asp}{Trp}{Leu}
Molecular Weight	1155.300
Application	Cancer Research

Overwijk, Willem W., et al. "gp100/pmel 17 is a murine tumor rejection antigen: induction of “self”-reactive, tumoricidal T cells using high-affinity, altered peptide ligand." The Journal of experimental medicine 188.2 (1998): 277-286.

Wang, Li-Xin, et al. "Interleukin-7-dependent expansion and persistence of melanoma-specific T cells in lymphodepleted mice lead to tumor regression and editing." Cancer research 65.22 (2005): 10569-10577.

Finkelstein, Steven E., et al. "Bedside to bench and back again: how animal models are guiding the development of new immunotherapies for cancer." Journal of leukocyte biology 76.2 (2004): 333-337.