C-Reactive Protein (CRP) (174-185)

Description:

CRP, an acute phase serum protein synthesized in response to inflammatory cytokines, has antitumor effects in animals. In vitro, the fragment CRP (174-185) shows similar activity by enhancing the tumoricidal activity of human monocytes and alveolar macrophages.

Sequence:

IYLGGPFSPNVL

General

References

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Name	C-Reactive Protein (CRP) (174-185)
Category	Cancer Research Peptides
One Letter Code	IYLGGPFSPNVL
Three Letter Code	{Ile}{Tyr}{Leu}{Gly}{Gly}{Pro}{Phe}{Ser}{Pro}{Asn}{Val}{Leu}
Molecular Weight	1276.500
Application	Cancer Research

Barna, Barbara P., et al. "Combination therapy with a synthetic peptide of C-reactive protein and interleukin 2: augmented survival and eradication of pulmonary metastases." Cancer Immunology, Immunotherapy 38.1 (1994): 38-42.

Barna, Barbara P., et al. "Therapeutic effects of a synthetic peptide of C-reactive protein in pre-clinical tumor models." Cancer Immunology, Immunotherapy 36.3 (1993): 171-176.

Thomassen, Mary Jane, et al. "Activation of human monocytes and alveolar macrophages by a synthetic peptide of C-reactive protein." Journal of immunotherapy with emphasis on tumor immunology: official journal of the Society for Biological Therapy 13.1 (1993): 1-6.