Bak BH3

Description:

This peptide is derived from the BH3 domain of Bak (Flu-BakBH3). It has high-affinity binding to a surface pocket of the Bcl-XL protein that is essential for its death antagonist function.

Sequence:

GQVGRQLAIIGDDINR

General

References

Comments (0)

Name	Bak BH3
Category	Cancer Research Peptides
One Letter Code	GQVGRQLAIIGDDINR
Three Letter Code	{Gly}{Gln}{Val}{Gly}{Arg}{Gln}{Leu}{Ala}{Ile}{Ile}{Gly}{Asp}{Asp}{Ile}{Asn}{Arg}
Molecular Weight	1724.900
Application	Cancer Research

Juin, Philippe, et al. "c-Myc functionally cooperates with Bax to induce apoptosis." Molecular and cellular biology 22.17 (2002): 6158-6169.