(Des-Arg⁹,Leu⁸)-Bradykinin

Description:

B₁ bradykinin receptor antagonist.

Sequence:

RPPGFSPL

General

References

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Name	(Des-Arg⁹,Leu⁸)-Bradykinin
Category	Bradykinin and Bradykinin-Potentiating Peptide (BPP)
One Letter Code	RPPGFSPL
Three Letter Code	{Arg}{Pro}{Pro}{Gly}{Phe}{Ser}{Pro}{Leu}
Molecular Weight	870.020
Application	Cardiovascular System & Diseases

Siltari, Aino, R. Korpela, and H. Vapaatalo. "Bradykinin–induced vasodilatation: Role of age, ACE1-inhibitory peptide, mas-and bradykinin receptors." Peptides 85 (2016): 46-55.

Ceravolo, Graziela S., et al. "An interaction of renin-angiotensin and kallikrein-kinin systems contributes to vascular hypertrophy in angiotensin II-induced hypertension: in vivo and in vitro studies." PloS one 9.11 (2014).

Marcon, R., et al. "Exacerbation of DSS‐induced colitis in mice lacking kinin B 1 receptors through compensatory up‐regulation of kinin B 2 receptors: the role of tight junctions and intestinal homeostasis." British journal of pharmacology 168.2 (2013): 389-402.

Ehrenfeld, Pamela, et al. "Activation of kinin B1 receptor increases the release of metalloproteases-2 and-9 from both estrogen-sensitive and-insensitive breast cancer cells." Cancer letters 301.1 (2011): 106-118.

Matus, C. E., et al. "Activation of kinin B1 receptor triggers differentiation of cultured human keratinocytes." British Journal of Dermatology 159.4 (2008): 792-803.

Lai, Josephine, et al. "Dynorphin A activates bradykinin receptors to maintain neuropathic pain." Nature neuroscience 9.12 (2006): 1534-1540.