[Des - Pro2] - Bradykinin

Description:

This peptide is an inhibitor for Angiotensin I Converting Enzyme (ACE I), derived from Bradykinin.

Sequence:

RPPGFSPFR
  • General
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  • Name [Des - Pro2] - Bradykinin
    Category Bradykinin and Bradykinin-Potentiating Peptide (BPP)
    One Letter Code RPPGFSPFR
    Three Letter Code {Arg}{Pro}{Pro}{Gly}{Phe}{Ser}{Pro}{Phe}{Arg}
    Molecular Weight 1060.200
    Application Cardiovascular System & DiseasesInflammation Research
    Charest-Morin, Xavier, et al. "Species-specific pharmacology of maximakinin, an amphibian homologue of bradykinin: putative prodrug activity at the human B2 receptor and peptidase resistance in rats." PeerJ 5 (2017): e2911.
    Niewiarowska-Sendo, Anna, Andrzej Kozik, and Ibeth Guevara-Lora. "Kinin peptides enhance inflammatory and oxidative responses promoting apoptosis in a Parkinson’s disease cellular model." Mediators of inflammation 2016 (2016).
    Siltari, Aino, R. Korpela, and H. Vapaatalo. "Bradykinin–induced vasodilatation: Role of age, ACE1-inhibitory peptide, mas-and bradykinin receptors." Peptides 85 (2016): 46-55.
    Alex, Anitha B., et al. "Pulmonary oedema producing toxin from Mesobuthus tamulus venom augments cardio-respiratory reflexes through B." Indian J Physiol Pharmacol 58.4 (2014): 312-318.
    Mukhopadhya, Anindya, et al. "Anti‐inflammatory effects of a casein hydrolysate and its peptide‐enriched fractions on TNFα‐challenged Caco‐2 cells and LPS‐challenged porcine colonic explants." Food science & nutrition 2.6 (2014): 712-723.
    Cattaruzza, Fiore, et al. "Serine proteases and protease‐activated receptor 2 mediate the proinflammatory and algesic actions of diverse stimulants." British journal of pharmacology 171.16 (2014): 3814-3826.
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