Lys-(Des-Arg⁹,Leu⁸)-Bradykinin

Description:

B₁ bradykinin receptor antagonist.

Sequence:

KRPPGFSPL
  • General
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  • Name Lys-(Des-Arg⁹,Leu⁸)-Bradykinin
    Category Bradykinin and Bradykinin-Potentiating Peptide (BPP)
    One Letter Code KRPPGFSPL
    Three Letter Code {Lys}{Arg}{Pro}{Pro}{Gly}{Phe}{Ser}{Pro}{Leu}
    Molecular Weight 998.190
    Application Cardiovascular System & Diseases
    Mejia, Astrid J., et al. "Intracellular signaling pathways involved in the release of IL-4 and VEGF from human keratinocytes by activation of kinin B 1 receptor: functional relevance to angiogenesis." Archives of dermatological research 307.9 (2015): 803-817.
    Gauthier, Kathryn M., Cody J. Cepura, and William B. Campbell. "ACE inhibition enhances bradykinin relaxations through nitric oxide and B1 receptor activation in bovine coronary arteries." Biological chemistry 394.9 (2013): 1205-1212.
    Matus, C. E., et al. "Activation of kinin B1 receptor triggers differentiation of cultured human keratinocytes." British Journal of Dermatology 159.4 (2008): 792-803.
    Farias, Nelson C., et al. "Ca2+-dependent K+ channels are targets for bradykinin B1 receptor ligands and for lipopolysaccharide in the rat aorta." European journal of pharmacology 525.1-3 (2005): 123-127.
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