Beta - Amyloid (12 - 28)

Description:

Aβ (12-28) enhances aggregation of full length Aβ (1-40).

Sequence:

VHHQKLVFFAEDVGSNK

General

References

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Name	Beta - Amyloid (12 - 28)
Category	Beta-Amyloidand Related Peptides
One Letter Code	VHHQKLVFFAEDVGSNK
Three Letter Code	{Val}{His}{His}{Gln}{Lys}{Leu}{Val}{Phe}{Phe}{Ala}{Glu}{Asp}{Val}{Gly}{Ser}{Asn}{Lys}
Molecular Weight	1955.200
Application	Alzheimer's Disease

Accardo, Angelo, et al. "Superhydrophobic surfaces boost fibril self-assembly of amyloid β peptides." ACS applied materials & interfaces 7.37 (2015): 20875-20884.

Hanenberg, Michael, et al. "Amyloid-β peptide-specific DARPins as a novel class of potential therapeutics for Alzheimer disease." Journal of Biological Chemistry 289.39 (2014): 27080-27089.

Scherzer-Attali, R., et al. "Naphthoquinone-tyrptophan reduces neurotoxic Aβ* 56 levels and improves cognition in Alzheimer's disease animal model." Neurobiology of disease 46.3 (2012): 663-672.

Frydman-Marom, Anat, et al. "Structural basis for inhibiting β-amyloid oligomerization by a non-coded β-breaker-substituted endomorphin analogue." ACS chemical biology 6.11 (2011): 1265-1276.

Scherzer-Attali, Roni, et al. "Complete phenotypic recovery of an Alzheimer's disease model by a quinone-tryptophan hybrid aggregation inhibitor." PloS one 5.6 (2010).