Amyloid β-Protein (25-35) amide

Description:

The amidation of amyloid β-protein (25-35) strongly reduce the amyloidogenic capacity of Aβ (25-35), while the neurotoxic activity is found to be independent of the aggregated state of the peptide.

Sequence:

GSNKGAIIGLM-NH₂

General

References

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Name	Amyloid β-Protein (25-35) amide
Category	Beta-Amyloidand Related Peptides
One Letter Code	GSNKGAIIGLM-NH₂
Three Letter Code	{Gly}{Ser}{Asn}{Lys}{Gly}{Ala}{Ile}{Ile}{Gly}{Leu}{Met}-NH₂
Molecular Weight	1059.300
Application	Alzheimer's Disease

Forloni, Gianluigi, et al. "Amidation of β‐amyloid peptide strongly reduced the amyloidogenic activity without alteration of the neurotoxicity." Journal of neurochemistry 69.5 (1997): 2048-2054.