Amyloid β-Protein (29-40)

Description:

Aβ 29-40, a C-terminal fragment of predominant Aβ 1-40, can induce the fusion of liposomes in vitro.

Sequence:

GAIIGLMVGGVV
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  • Name Amyloid β-Protein (29-40)
    Category Beta-Amyloidand Related Peptides
    One Letter Code GAIIGLMVGGVV
    Three Letter Code {Gly}{Ala}{Ile}{Ile}{Gly}{Leu}{Met}{Val}{Gly}{Gly}{Val}{Val}
    Molecular Weight 1085.380
    Application Alzheimer's Disease
    Hanenberg, Michael, et al. "Amyloid-β peptide-specific DARPins as a novel class of potential therapeutics for Alzheimer disease." Journal of Biological Chemistry 289.39 (2014): 27080-27089.
    Maloney, Bryan, and Debomoy K. Lahiri. "The Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: characterizing a new regulatory motif." Gene 488.1-2 (2011): 1-12.
    Bailey, Jason A., et al. "Functional activity of the novel Alzheimer's amyloid β-peptide interacting domain (AβID) in the APP and BACE1 promoter sequences and implications in activating apoptotic genes and in amyloidogenesis." Gene 488.1-2 (2011): 13-22.
    Sole-Domenech, Santiago, et al. "Analysis of opioid and amyloid peptides using time-of-flight secondary ion mass spectrometry." Analytical chemistry 82.5 (2010): 1964-1974.
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