Beta - Amyloid (22 - 35)

Description:

Aβ (22-35) forms amyloid fibrils in vitro

Sequence:

EDVGSNKGAIIGLM
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  • Name Beta - Amyloid (22 - 35)
    Category Beta-Amyloidand Related Peptides
    One Letter Code EDVGSNKGAIIGLM
    Three Letter Code {Glu}{Asp}{Val}{Gly}{Ser}{Asn}{Lys}{Gly}{Ala}{Ile}{Ile}{Gly}{Leu}{Met}
    Molecular Weight 1403.600
    Application Alzheimer's Disease
    McManus, Meagan J., Michael P. Murphy, and James L. Franklin. "The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease." Journal of Neuroscience 31.44 (2011): 15703-15715.
    Fu, Ai-Ling, Zhao-Hui Dong, and Man-Ji Sun. "Protective effect of N-acetyl-L-cysteine on amyloid β-peptide-induced learning and memory deficits in mice." Brain research 1109.1 (2006): 201-206.
    Takadera, Tsuneo, et al. "Toxic effect of a β-amyloid peptide (β22–35) on the hippocampal neuron and its prevention." Neuroscience letters 161.1 (1993): 41-44.
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