[Gly22] - beta - Amyloid (1 - 42), E22G Arctic Mutation

Description:

This is amino acids 1 to 40 fragment of the mutant form of beta-amyloid found in Arctic heredity with glycine substituted for glutamic acid at position 22 .

Sequence:

DAEFRHDSGYEVHHQKLVFFAGDVGSNKGAIIGLMVGGVVIA
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  • Name [Gly22] - beta - Amyloid (1 - 42), E22G Arctic Mutation
    Category Beta-Amyloidand Related Peptides
    One Letter Code DAEFRHDSGYEVHHQKLVFFAGDVGSNKGAIIGLMVGGVVIA
    Three Letter Code {Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}{Val}{His}{His}{Gln}{Lys}{Leu}{Val}{Phe}{Phe}{Ala}{Gly}{Asp}{Val}{Gly}{Ser}{Asn}{Lys}{Gly}{Ala}{Ile}{Ile}{Gly}{Leu}{Met}{Val}{Gly}{Gly}{Val}{Val}{Ile}{Ala}
    Molecular Weight 4442.100
    Application
    Yamamoto, Naoki, et al. "A Ganglioside-induced Toxic Soluble Aβ Assembly ITS ENHANCED FORMATION FROM AβBEARING THE ARCTIC MUTATION." Journal of Biological Chemistry 282.4 (2007): 2646-2655.
    Van Nostrand, William E., et al. "Pathogenic effects of D23N Iowa mutant amyloid β-protein." Journal of Biological Chemistry 276.35 (2001): 32860-32866.
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