(Asp³⁷)-Amyloid β-Protein (1-42)

Description:

The mutant does not show the aggregation behavior of WT Aβ 42 nor its neurotoxicity.

Sequence:

DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGVMVDGVVIA

General

References

Comments (0)

Name	(Asp³⁷)-Amyloid β-Protein (1-42)
Category	Beta-Amyloidand Related Peptides
One Letter Code	DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGVMVDGVVIA
Three Letter Code	{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}{Val}{His}{His}{Gln}{Lys}{Leu}{Val}{Phe}{Phe}{Ala}{Glu}{Asp}{Val}{Gly}{Ser}{Asn}{Lys}{Gly}{Ala}{Ile}{Ile}{Gly}{Leu}{Met}{Val}{Asp}{Gly}{Val}{Val}{Ile}{Ala}
Molecular Weight	4572.140
Application	Alzheimer's Disease

Kanski, Jaroslaw, Marina Aksenova, and D. Allan Butterfield. "The hydrophobic environment of Met35 of Alzheimer's Aβ (1–42) is important for the neurotoxic and oxidative properties of the peptide." Neurotoxicity Research 4.3 (2002): 219-223.