Beta - Amyloid (1 - 42)

Description:

Beta-Amyloid (1-42), a major component of amyloid plaques, accumulates in neurons of Alzheimer’s disease brains.

Sequence:

DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

General

References

Comments (0)

Name	Beta - Amyloid (1 - 42)
Category	Beta-Amyloidand Related Peptides
One Letter Code	DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Three Letter Code	{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}{Val}{His}{His}{Gln}{Lys}{Leu}{Val}{Phe}{Phe}{Ala}{Glu}{Asp}{Val}{Gly}{Ser}{Asn}{Lys}{Gly}{Ala}{Ile}{Ile}{Gly}{Leu}{Met}{Val}{Gly}{Gly}{Val}{Val}{Ile}{Ala}
Molecular Weight	4514.100
Application	Alzheimer's DiseaseAntimicrobial & Antiviral Peptides

Bosson, Anthony, et al. "TRPA1 channels promote astrocytic Ca 2+ hyperactivity and synaptic dysfunction mediated by oligomeric forms of amyloid-β peptide." Molecular neurodegeneration 12.1 (2017): 53.

Choi, Heesun, et al. "Increased acetylation of Peroxiredoxin1 by HDAC6 inhibition leads to recovery of Aβ-induced impaired axonal transport." Molecular neurodegeneration 12.1 (2017): 23.

van Gijsel-Bonnello, Manuel, et al. "Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer’s disease: alleviation by pantethine." PloS one 12.4 (2017).

Stock, Amanda J., et al. "The role of neutrophil proteins on the amyloid Beta-RAGE Axis." PloS one 11.9 (2016).

Nabers, Andreas, et al. "An infrared sensor analysing label‐free the secondary structure of the Abeta peptide in presence of complex fluids." Journal of biophotonics 9.3 (2016): 224-234.

Wakx, Anaïs, et al. "Amyloid β peptide induces apoptosis through P2X7 cell death receptor in retinal cells: modulation by marine omega-3 fatty acid DHA and EPA." Applied biochemistry and biotechnology 178.2 (2016): 368-381.