(Des-Glu²²)-Amyloid β-Protein (1-42)

Description:

The Osaka (E22delta) mutation of Amyloid β promotes β-sheet transformation, radical production, and synaptotoxicity, but not neurotoxicity.

Sequence:

DAEFRHDSGYEVHHQKLVFFADVGSNKGAIIGLMVGGVVIA

General

References

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Name	(Des-Glu²²)-Amyloid β-Protein (1-42)
Category	Beta-Amyloidand Related Peptides
One Letter Code	DAEFRHDSGYEVHHQKLVFFADVGSNKGAIIGLMVGGVVIA
Three Letter Code	{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}{Val}{His}{His}{Gln}{Lys}{Leu}{Val}{Phe}{Phe}{Ala}{Asp}{Val}{Gly}{Ser}{Asn}{Lys}{Gly}{Ala}{Ile}{Ile}{Gly}{Leu}{Met}{Val}{Gly}{Gly}{Val}{Val}{Ile}{Ala}
Molecular Weight	4384.990
Application	Alzheimer's Disease

Suzuki, Takayuki, et al. "E22Δ mutation in amyloid β-protein promotes β-sheet transformation, radical production, and synaptotoxicity, but not neurotoxicity." International Journal of Alzheimer’s Disease 2011 (2011).