Adrenomedullin (22 - 52) (human)

Description:

ADM (22-52) is known as an adrenomedullin receptor antagonist and a cardiac depressant factor

Sequence:

TVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH2
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  • Name Adrenomedullin (22 - 52) (human)
    Category Adrenomedullin Peptides
    One Letter Code TVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH2
    Three Letter Code {Thr}{Val}{Gln}{Lys}{Leu}{Ala}{His}{Gln}{Ile}{Tyr}{Gln}{Phe}{Thr}{Asp}{Lys}{Asp}{Lys}{Asp}{Asn}{Val}{Ala}{Pro}{Arg}{Ser}{Lys}{Ile}{Ser}{Pro}{Gln}{Gly}{Tyr}-NH2
    Molecular Weight 3576.000
    Application Cardiovascular System & Diseases
    Nikitenko, Leonid L., et al. "Adrenomedullin haploinsufficiency predisposes to secondary lymphedema." Journal of Investigative Dermatology 133.7 (2013): 1768-1776.
    Liverani, Elisabetta, Julie D. McLeod, and Carolyn Paul. "Adrenomedullin receptors on human T cells are glucocorticoid-sensitive." International immunopharmacology 14.1 (2012): 75-81.
    Aslam, M., et al. "Intermedin (adrenomedullin2) stabilizes the endothelial barrier and antagonizes thrombin‐induced barrier failure in endothelial cell monolayers." British journal of pharmacology 165.1 (2012): 208-222.
    Musson, David S., et al. "Adrenomedullin is expressed during rodent dental tissue development and promotes cell growth and mineralization." Biology of the Cell 102.3 (2010): 145-157.
    Kioon, Marie-Dominique Ah, et al. "Adrenomedullin increases fibroblast-like synoviocyte adhesion to extracellular matrix proteins by upregulating integrin activation." Arthritis research & therapy 12.5 (2010): R190.
    Kim, Su-Mi, et al. "Adrenomedullin protects against hypoxia/reoxygenation‐induced cell death by suppression of reactive oxygen species via thiol redox systems." FEBS letters 584.1 (2010): 213-218.
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