Beta - Amyloid (1 - 9)

Description:

This is the N-terminal fragment of Aβ peptide amino acids 1 to 9, contains a functional B cell epitope, but lacks known T cell epitopes. It is an attractive candidate for the development of β-Amyloid vaccine

Sequence:

DAEFRHDSG
  • General
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  • Name Beta - Amyloid (1 - 9)
    Category Beta-Amyloidand Related Peptides
    One Letter Code DAEFRHDSG
    Three Letter Code {Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}
    Molecular Weight 1033.000
    Application Alzheimer's Disease
    Paravastu, Anant K., Aneta T. Petkova, and Robert Tycko. "Polymorphic fibril formation by residues 10–40 of the Alzheimer’s β-amyloid peptide." Biophysical journal 90.12 (2006): 4618-4629.
    Zamora, Eduardo, et al. "Papillomavirus-like particles are an effective platform for amyloid-β immunization in rabbits and transgenic mice." The Journal of Immunology 177.4 (2006): 2662-2670.
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