Ac-Amyloid β/A4 Protein Precursor₇₇₀ (96-110) (cyclized)

Description:

This cyclized peptide blocks the heparan sulfate proteoglycan-dependent stimulatory effect of APP on neurite outgrowth.

Sequence:

Ac-NWCKRGRKQCKTHPH-NH₂ (Disulfide bridge: 3-10)

General

References

Comments (0)

Name	Ac-Amyloid β/A4 Protein Precursor₇₇₀ (96-110) (cyclized)
Category	Beta-Amyloidand Related Peptides
One Letter Code	Ac-NWCKRGRKQCKTHPH-NH₂ (Disulfide bridge: 3-10)
Three Letter Code	Ac-{Asn}{Trp}{Cys}{Lys}{Arg}{Gly}{Arg}{Lys}{Gln}{Cys}{Lys}{Thr}{His}{Pro}{His}-NH₂ (Disulfide bridge: 3-10) (Disulfide bridge: 3-10)
Molecular Weight	1918.240
Application	Alzheimer's Disease

Small, David H., et al. "A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth." Journal of Neuroscience14.4 (1994): 2117-2127.