EK1

Description:

EK1, the optimized form of OC43-HR2P, showed substantially improved pan-CoV fusion inhibitory activity and pharmaceutical properties.

Sequence:

SLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKEL
  • General
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  • Name EK1
    Category COVID-19
    One Letter Code SLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKEL
    Three Letter Code { Ser }{ Leu }{ Asp }{ Gln }{ Ile }{ Asn }{ Val }{ Thr }{ Phe }{ Leu }{ Asp }{ Leu }{ Glu }{ Tyr }{ Glu }{ Met }{ Lys }{ Lys }{ Leu }{ Glu }{ Glu }{ Ala }{ Ile }{ Lys }{ Lys }{ Leu }{ Glu }{ Glu }{ Ser }{ Tyr }{ Ile }{ Asp }{ Leu }{ Lys }{ Glu }{ Leu }
    Molecular Weight 4331.950
    Application COVID-19
    Xia, S. et al. A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Sci. Adv. 5, eaav4580 (2019).
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