EK1C4

Description:

EK1C4 is one of a series of lipopeptides derived from EK1 , EK1C4 was the most potent fusion inhibitor against SARS-CoV-2 S protein-mediated membrane fusion and pseudovirus infection.

Sequence:

SLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKEL-GSGSG-PEG4-Chol

General

References

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Name	EK1C4
Category	COVID-19
One Letter Code	SLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKEL-GSGSG-PEG4-Chol
Three Letter Code	{ Ser }{ Leu }{ Asp }{ Gln }{ Ile }{ Asn }{ Val }{ Thr }{ Phe }{ Leu }{ Asp }{ Leu }{ Glu }{ Tyr }{ Glu }{ Met }{ Lys }{ Lys }{ Leu }{ Glu }{ Glu }{ Ala }{ Ile }{ Lys }{ Lys }{ Leu }{ Glu }{ Glu }{ Ser }{ Tyr }{ Ile }{ Asp }{ Leu }{ Lys }{ Glu }{ Leu }-{ Gly }{ Ser }{ Gly }{ Ser }{ Gly }-PEG4-Chol
Molecular Weight	4677.260
Application	COVID-19

Shuai Xia, Meiqin Liu et al. "Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion". Cell Research volume 30, 343–355 (2020).