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Ac-(Pro¹⁸,Asp²¹)-Amyloid β-Protein (17-21), amide
| Name | Ac-(Pro¹⁸,Asp²¹)-Amyloid β-Protein (17-21), amide |
| Category | Beta-Amyloidand Related Peptides |
| One Letter Code | Ac-LPFFD-NH₂ |
| Three Letter Code | Ac-{Leu}{Pro}{Phe}{Phe}{Asp}-NH₂ |
| Molecular Weight | 678.790 |
| Application | Alzheimer's Disease |
| Chacon, M. A., et al. "β-sheet breaker peptide prevents A β-induced spatial memory impairments with partial reduction of amyloid deposits." Molecular psychiatry 9.10 (2004): 953-961. |
| Permanne, B., et al. "Van Dopre J, Dewachter I, Banks WA, Van Leuven F, Soto C. Reduction of amyloid load and cerebral damage in a transgenic mouse model of Alzheimer's disease by treatment with a β-sheet breaker peptide." FASEB J 16 (2002): 860-862. |