(Pyr¹¹)-Amyloid β-Protein (11-40)

Description:

(Pyr¹¹)-Amyloid β-Protein (11-40) is used to study the generality of fibrillogenesis-related helix formation.

Sequence:

{pGLU}VHHQKLVFFAEDVGSNKGAIIGLMVGGVV

General

References

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Name	(Pyr¹¹)-Amyloid β-Protein (11-40)
Category	Beta-Amyloidand Related Peptides
One Letter Code	{pGLU}VHHQKLVFFAEDVGSNKGAIIGLMVGGVV
Three Letter Code	{pGLU}{Val}{His}{His}{Gln}{Lys}{Leu}{Val}{Phe}{Phe}{Ala}{Glu}{Asp}{Val}{Gly}{Ser}{Asn}{Lys}{Gly}{Ala}{Ile}{Ile}{Gly}{Leu}{Met}{Val}{Gly}{Gly}{Val}{Val}
Molecular Weight	3133.670
Application	Alzheimer's Disease

Perez-Garmendia, Roxanna, and Goar Gevorkian. "Pyroglutamate-modified amyloid beta peptides: emerging targets for Alzheimer s disease immunotherapy." Current neuropharmacology 11.5 (2013): 491-498.

Kirkitadze, Marina D., Margaret M. Condron, and David B. Teplow. "Identification and characterization of key kinetic intermediates in amyloid β-protein fibrillogenesis." Journal of molecular biology 312.5 (2001): 1103-1119.

Mok, Su San, et al. "Aβ peptides and calcium influence secretion of the amyloid protein precursor from chick sympathetic neurons in culture." Journal of neuroscience research 61.4 (2000): 449-457.