Substance P (1-7)

Description:

This amino-terminal fragment of substance P exerts depressor and bradycardic effects when applied to the nucleus tractus solitarius. It was also shown that this fragment, contrary to substance P, may reduce signs of opioid withdrawal in mice.

Sequence:

RPKPQQF
  • General
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  • Name Substance P (1-7)
    Category Substance P and Analogs
    One Letter Code RPKPQQF
    Three Letter Code {Arg}{Pro}{Lys}{Pro}{Gln}{Gln}{Phe}
    Molecular Weight 900.050
    Application Opioid Research
    A.K.Chappa et al.,J. Pharm. Biomed. Anal.,43,1409(2007)
    A.L.Freed et al.,J. Neurosci. Methods,109,23(2001)
    A.L.Freed et al.,Electrophoresis,22,3778 (2001)
    Q.Zhou et al.,Peptides,24,147(2003)
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