Beta - Amyloid A4 Protein Precursor (740 - 770), APP (C31)

Description:

This 31-amino acid peptide is the C-terminal fragment of amyloid precursor protein(APP) also known as C31.The resultant C31 peptide is a potent inducer of apoptosis.

Sequence:

AAVTPEERHLSKMQQNGYENPTYKFFEQMQN

General

References

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Name	Beta - Amyloid A4 Protein Precursor (740 - 770), APP (C31)
Category	Beta-Amyloidand Related Peptides
One Letter Code	AAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Three Letter Code	{Ala}{Ala}{Val}{Thr}{Pro}{Glu}{Glu}{Arg}{His}{Leu}{Ser}{Lys}{Met}{Gln}{Gln}{Asn}{Gly}{Tyr}{Glu}{Asn}{Pro}{Thr}{Tyr}{Lys}{Phe}{Phe}{Glu}{Gln}{Met}{Gln}{Asn}
Molecular Weight	3717.100
Application	Alzheimer's Disease

Chen, Yuzhi, et al. "APP-BP1 mediates APP-induced apoptosis and DNA synthesis and is increased in Alzheimer's disease brain." The Journal of cell biology 163.1 (2003): 27-33.

Lu, Daniel C., et al. "A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor." Nature medicine 6.4 (2000): 397-404.