(D-Arg¹,D-Trp⁷·⁹,Leu¹¹)-Substance P

Description:

Spantide I is a high potent substance P antagonist. It has a weak spasmogenic and a poor histamine releasing effect.

Sequence:

{D-Arg}PKPQQ{D-Trp}F{D-Trp}LL-NH₂
  • General
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  • Name (D-Arg¹,D-Trp⁷·⁹,Leu¹¹)-Substance P
    Category Substance P and Analogs
    One Letter Code {D-Arg}PKPQQ{D-Trp}F{D-Trp}LL-NH₂
    Three Letter Code {D-Arg}{Pro}{Lys}{Pro}{Gln}{Gln}{D-Trp}{Phe}{D-Trp}{Leu}{Leu}-NH₂
    Molecular Weight 1497.810
    Application
    K.Lucas et al.,J. Immunol.,189,1237(2012)
    S.W.Sio et al.,Am. J. Respir. Crit. Care Med.,181,36(2010)
    J.Poels et al.,Peptides,30,545(2009)
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