(D-Arg¹,D-Trp⁵·⁷·⁹,Leu¹¹)-Substance P

Description:

This substance P analog is a very potent broad-spectrum neuropeptide inhibitor for small cell lung cancer (SCLC) cell growth in vitro (IC₅₀ = 5 µM).

Sequence:

{D-Arg}PKP{D-Trp}Q{D-Trp}F{D-Trp}LL-NH₂
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  • Name (D-Arg¹,D-Trp⁵·⁷·⁹,Leu¹¹)-Substance P
    Category Substance P and Analogs
    One Letter Code {D-Arg}PKP{D-Trp}Q{D-Trp}F{D-Trp}LL-NH₂
    Three Letter Code {D-Arg}{Pro}{Lys}{Pro}{D-Trp}{Gln}{D-Trp}{Phe}{D-Trp}{Leu}{Leu}-NH₂
    Molecular Weight 1555.890
    Application Cancer Research
    S.Guha et al.,Cancer Res.,65,2738 (2005)
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