IRBP, Interphotoreceptor Retinoid Binding Protein Fragment

Description:

This 20-residue peptide, a major pathogenic T-cell epitope (161–180), is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP). It has been shown to induce posterior uveitis (EAU).

Sequence:

SGIPYIISYLHPGNTILHVD

General

References

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Name	IRBP, Interphotoreceptor Retinoid Binding Protein Fragment
Category	Signal Transduction Peptides
One Letter Code	SGIPYIISYLHPGNTILHVD
Three Letter Code	{Ser}{Gly}{Ile}{Pro}{Tyr}{Ile}{Ile}{Ser}{Tyr}{Leu}{His}{Pro}{Gly}{Asn}{Thr}{Ile}{Leu}{His}{Val}{Asp}
Molecular Weight	2209.500
Application	Signal Transduction

Sonoda, K. et al. J. Immunol. 171, 2652 (2003);

Read, RW. and SR. Barnum, ARVO Meeting Abstracts 43, 2281 (2002);

Karabekian, Z. et al. Invest. Ophthalmol. Vis. Sci. 46, 3769 (2005).