Bax BH3 peptide (55 - 74) (wild type)

Description:

Bax BH3 belongs to the Bcl-2 protein family, it can promote cytochrome c release from isolated mitochondria and induce apoptosis in a variety of cell line models.

Sequence:

STKKLSECLKRIGDELDSNM

General

References

Comments (0)

Name	Bax BH3 peptide (55 - 74) (wild type)
Category	Apoptosis Peptides
One Letter Code	STKKLSECLKRIGDELDSNM
Three Letter Code	{Ser}{Thr}{Lys}{Lys}{Leu}{Ser}{Glu}{Cys}{Leu}{Lys}{Arg}{Ile}{Gly}{Asp}{Glu}{Leu}{Asp}{Ser}{Asn}{Met}
Molecular Weight	2267.600
Application	Cancer Research Peptides, Apoptosis Peptides

Shangary, Sanjeev, et al. "Sequence and helicity requirements for the proapoptotic activity of Bax BH3 peptides." Molecular cancer therapeutics 3.11 (2004): 1343-1354.

Shangary, Sanjeev, and Daniel E. Johnson. "Peptides derived from BH3 domains of Bcl-2 family members: a comparative analysis of inhibition of Bcl-2, Bcl-xL and Bax oligomerization, induction of cytochrome c release, and activation of cell death." Biochemistry 41.30 (2002): 9485-9495.