Pro - apoptotic Peptide, klaklakklaklak, 5 - FAM - labeled

Description:

This is a pro-apoptotic peptide contained D-amino acids, labeled 5-fam.This amphiphilic peptide is toxic to eukaryotic cells and it destroys the mitochondrial membrane during receptor-mediated cell internalization, leading to programmed cell death.

Sequence:

5-FAM-{D-Lys}{D-Leu}{D-Ala}{D-Lys}{D-Leu}{D-Ala}{D-Lys}{D-Lys}{D-Leu}{D-Ala}{D-Lys}{D-Leu}{D-Ala}{D-Lys}-NH2

General

References

Comments (0)

Name	Pro - apoptotic Peptide, klaklakklaklak, 5 - FAM - labeled
Category	Apoptosis Peptides
One Letter Code	5-FAM-{D-Lys}{D-Leu}{D-Ala}{D-Lys}{D-Leu}{D-Ala}{D-Lys}{D-Lys}{D-Leu}{D-Ala}{D-Lys}{D-Leu}{D-Ala}{D-Lys}-NH2
Three Letter Code	5-FAM-{D-Lys}{D-Leu}{D-Ala}{D-Lys}{D-Leu}{D-Ala}{D-Lys}{D-Lys}{D-Leu}{D-Ala}{D-Lys}{D-Leu}{D-Ala}{D-Lys}-NH2
Molecular Weight	1881.300
Application	Fluorescent Labeled Peptides

Marks, Alexandra J., et al. "Selective apoptotic killing of malignant hemopoietic cells by antibody-targeted delivery of an amphipathic peptide." Cancer research 65.6 (2005): 2373-2377.

Kolonin, Mikhail G., et al. "Reversal of obesity by targeted ablation of adipose tissue." Nature medicine 10.6 (2004): 625-632.